ECCU (E-cadherin/catenin) complex and its role in carcinogenesis
Introduction:One of the main characteristics of cancer is uncontrolled cell proliferation as well as loss of cells adhesion in the case of metastases.Cadherins and catenins are the molecules responsible for cell-to-cell interaction.Together, they form a complex called ECCU (E-cadherin/catenin complex) which maintains the proper tissue structure.How